Ticker · CUSIP 98420N105

XENE

XENON PHARMACEUTICALS INC

Healthcare·Biotechnology

···Share

Holders (tracked)

Combined shares

8,469,044

Combined value

$379.58M

Last close

$59.70

Quarter

2025Q4

Price is +33.2% vs the avg quarter-end implied price across tracked holders.

Price · 1Y$59.70+24.59 (+70.04%)H $62.76 · L $28.49 · Avg Vol 1.1M

Position opened

Tracked holders · last 8 quarters

+3 vs previous quarter over the last 8.

SEC event timeline

15 events

Ken Griffin (Citadel Advisors) added2026-02-17
+362,115 shares · 2025Q4
Position
D.E. Shaw & Co. trimmed2026-02-17
−17,604 shares · 2025Q4
Position
Two Sigma Investments opened position2026-02-17
+436,743 shares · 2025Q4
Position
Izzy Englander (Millennium Mgmt) trimmed2026-02-17
−748,951 shares · 2025Q4
Position
Steve Cohen (Point72) opened position2026-02-17
+18,600 shares · 2025Q4
Position
T. Rowe Price added2026-02-17
+820,608 shares · 2025Q4
Position
Wellington Management added2026-02-17
+1,154,922 shares · 2025Q4
Position
Paul Tudor Jones (Tudor Investment) opened position2026-02-17
+254,002 shares · 2025Q4
Position
Renaissance Technologies exited2026-02-12
−5,200 shares · 2025Q4
Position
Wellington Management added2025-11-14
+1,435,096 shares · 2025Q3
Position
Izzy Englander (Millennium Mgmt) added2025-11-14
+501,172 shares · 2025Q3
Position
Ron Baron (Baron Capital / BAMCO) trimmed2025-11-14
−26,000 shares · 2025Q3
Position
D.E. Shaw & Co. trimmed2025-11-14
−93,328 shares · 2025Q3
Position
T. Rowe Price added2025-11-14
+3,757 shares · 2025Q3
Position
Renaissance Technologies trimmed2025-11-13
−3,400 shares · 2025Q3
Position

Insider activity

No insider transactions in the last 30 days.

View full insider history for XENE →

Follow-the-investor returns

If you'd copied each holder of XENE…

Cost basis inferred from each manager's quarter-over-quarter position changes. Sorted by % return on the position they're still holding.

Investor	First in	Cost basis	Return	Position value today
D.E. Shaw & Co.	2018Q4	$35.37	+68.8%	$1.8M
Steve Cohen (Point72)	2016Q1	$35.92	+66.2%	$555K
Steve Cohen (Point72)	2016Q1	$35.92	+66.2%	$555K
Ron Baron (Baron Capital / BAMCO)	2021Q4	$36.26	+64.6%	$1.8M
Wellington Management	2023Q1	$41.97	+42.3%	$284.5M
Two Sigma Investments	2018Q3	$43.22	+38.1%	$26.1M
Izzy Englander (Millennium Mgmt)	2016Q4	$43.90	+36.0%	$37.9M
T. Rowe Price	2025Q2	$44.21	+35.0%	$51.5M
Paul Tudor Jones (Tudor Investment)	2022Q2	$44.61	+33.8%	$15.2M
Paul Tudor Jones (Tudor Investment)	2022Q2	$44.61	+33.8%	$15.2M
Ken Griffin (Citadel Advisors)	2019Q1	$44.75	+33.4%	$78.9M
Ken Griffin (Citadel Advisors)	2019Q1	$44.75	+33.4%	$78.9M
Ken Griffin (Citadel Advisors)	2019Q1	$44.75	+33.4%	$78.9M

Who moved on this name in 2025Q4

Position changes reported for the latest quarter, grouped by direction.

New positions3

Two Sigma Investments
+436,743
$19.6M
Paul Tudor Jones (Tudor Investment)
+254,002
$11.4M
Steve Cohen (Point72)
+18,600
$834K

Added to3

Wellington Management
+1,154,922
$51.8M
Ken Griffin (Citadel Advisors)
+362,115
$16.2M
T. Rowe Price
+820,608
$37K

Trimmed2

Izzy Englander (Millennium Mgmt)
−748,951
$33.6M
D.E. Shaw & Co.
−17,604
$789K

Exited1

Renaissance Technologies
−5,200
$209K

Institutional ownership over time

Distinct super-investors holding this ticker · combined dollar value, by quarter.

Quarter	Holders	Shares	Combined value	Δ holders
2022Q1	9	5,112,867	$156.3M	—
2022Q2	9	4,305,104	$131.0M	—
2022Q3	9	4,913,489	$177.4M	—
2022Q4	8	4,319,416	$170.3M	-1
2023Q1	12	3,476,883	$124.4M	+4
2023Q2	10	3,143,027	$121.0M	-2
2023Q3	12	3,275,862	$111.9M	+2
2023Q4	10	4,970,873	$229.0M	-2
2024Q1	11	8,168,664	$351.7M	+1
2024Q2	12	7,964,530	$310.5M	+1
2024Q3	11	5,807,925	$228.7M	-1
2024Q4	9	1,172,939	$46.0M	-2
2025Q1	10	5,578,271	$187.2M	+1
2025Q2	9	3,479,959	$108.9M	-1
2025Q3	10	6,194,909	$248.7M	+1
2025Q4	13	8,469,044	$379.6M	+3

Who owns XENE

13 super-investors · 2025Q4

Tracked stake

8.47M

Combined value

$380M

% of shares outstanding

—

shares-out unknown

Quarter action mix

New5Added5Trim2Held1

#	Manager	Shares	Value	% of book	Last action
1	Wellington Management	4.76M	$214M	0.0%	Added+1.15M
2	Ken Griffin Citadel Advisors	1.32M	$59M	0.0%	Added+362.1K
3	T. Rowe Price	862.3K	$39M	0.0%	Added+820.6K
4	Izzy Englander Millennium Mgmt	635.1K	$28M	0.0%	Trim−749.0K
5	Two Sigma Investments	436.7K	$20M	0.0%	New+436.7K
6	Paul Tudor Jones Tudor Investment	254.0K	$11M	0.0%	New+254.0K
7	Ken Griffin Citadel Advisors	61.6K	$3M	0.0%	Added+362.1K
8	Ken Griffin Citadel Advisors	46.9K	$2M	0.0%	Added+362.1K
9	D.E. Shaw & Co.	30.9K	$1M	0.0%	Trim−17.6K
10	Ron Baron Baron Capital / BAMCO	30.0K	$1M	0.0%	Held
11	Steve Cohen Point72	9.3K	$417K	0.0%	New+18.6K
12	Steve Cohen Point72	9.3K	$417K	0.0%	New+18.6K
13	Paul Tudor Jones Tudor Investment	7.0K	$314K	0.0%	New+254.0K

Recent moves

20 transactions

NEWTwo Sigma Investments
+436,743 · 2025Q4
TRIMD.E. Shaw & Co.
−17,604 · 2025Q4
ADDWellington Management
+1,154,922 · 2025Q4
ADDKen Griffin (Citadel Advisors)
+362,115 · 2025Q4
TRIMIzzy Englander (Millennium Mgmt)
−748,951 · 2025Q4
NEWSteve Cohen (Point72)
+18,600 · 2025Q4
NEWPaul Tudor Jones (Tudor Investment)
+254,002 · 2025Q4
ADDT. Rowe Price
+820,608 · 2025Q4
SOLDRenaissance Technologies
−5,200 · 2025Q4
TRIMD.E. Shaw & Co.
−93,328 · 2025Q3
ADDT. Rowe Price
+3,757 · 2025Q3
ADDIzzy Englander (Millennium Mgmt)
+501,172 · 2025Q3
ADDWellington Management
+1,435,096 · 2025Q3
TRIMRon Baron (Baron Capital / BAMCO)
−26,000 · 2025Q3
TRIMRenaissance Technologies
−3,400 · 2025Q3
SOLDTwo Sigma Investments
−236,983 · 2025Q2
SOLDSteve Cohen (Point72)
−209,759 · 2025Q2
NEWT. Rowe Price
+37,935 · 2025Q2
ADDIzzy Englander (Millennium Mgmt)
+648,779 · 2025Q2
TRIMD.E. Shaw & Co.
−10,405 · 2025Q2

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