Ticker · CUSIP 829401108

SION

SIONNA THERAPEUTICS INC
···Share
Holders (tracked)
7
Combined shares
5,244,914
Combined value
$215.78M
Last close
$43.54
Quarter
2025Q4
Price · 1Y$43.54+32.47 (+293.32%)H $45.24 · L $11.07 · Avg Vol 266K
Insider sellPosition opened
$10.00$20.00$30.00$40.00VolJul 25Oct 25Jan 26Apr 26
Tracked holders · last 8 quarters
+1 vs previous quarter over the last 4.
752025Q12025Q4
Price is +5.8% vs the avg quarter-end implied price across tracked holders.

SEC event timeline

17 events
  1. ORBIMED ADVISORS LLC
    2026-04-16
    Sold $10.29M @ $45.34
    Insider sell
  2. Thompson Peter A.
    2026-04-16
    Sold $10.29M @ $45.34
    Insider sell
  3. Thompson Peter A.
    2026-04-15
    Sold $10.53M @ $44.64
    Insider sell
  4. ORBIMED ADVISORS LLC
    2026-04-15
    Sold $10.53M @ $44.64
    Insider sell
  5. ORBIMED ADVISORS LLC
    2026-04-14
    Sold $2.13M @ $44.51
    Insider sell
  6. Thompson Peter A.
    2026-04-14
    Sold $2.13M @ $44.51
    Insider sell
  7. +5,742 shares · 2025Q4
    Position
  8. +6,400 shares · 2025Q4
    Position
  9. +1,051,402 shares · 2025Q4
    Position
  10. −133,539 shares · 2025Q4
    Position
  11. +193,613 shares · 2025Q4
    Position
  12. −3,887 shares · 2025Q4
    Position
  13. −14,600 shares · 2025Q4
    Position
  14. +42,234 shares · 2025Q3
    Position
  15. +200,051 shares · 2025Q3
    Position
  16. −223,478 shares · 2025Q3
    Position
  17. −11,400 shares · 2025Q3
    Position

Insider activity

Last 30 days
Net (open-market)
−$45.89M
Buys
0 · $0
Sells
6 · $45.89M
Unique insiders
2
DateInsiderCodeSharesPriceValue
04-16ORBIMED ADVISORS LLC
Director
S226,906$45.34$10.29M
04-16Thompson Peter A.
Director
S226,906$45.34$10.29M
04-15Thompson Peter A.
Director
S235,863$44.64$10.53M
04-15ORBIMED ADVISORS LLC
Director
S235,863$44.64$10.53M
04-14ORBIMED ADVISORS LLC
Director
S47,814$44.51$2.13M
04-14Thompson Peter A.
Director
S47,814$44.51$2.13M
Follow-the-investor returns
If you'd copied each holder of SION…
Cost basis inferred from each manager's quarter-over-quarter position changes. Sorted by % return on the position they're still holding.
InvestorFirst inCost basisReturnPosition value today
Two Sigma Investments2025Q1$10.46+316.3%$279K
Andreas Halvorsen (Viking Global)2025Q1$10.98+296.4%$139.1M
T. Rowe Price2025Q1$17.61+147.3%$36.2M
Izzy Englander (Millennium Mgmt)2025Q1$28.17+54.6%$3.5M
Wellington Management2025Q3$29.41+48.0%$1.7M
Ken Griffin (Citadel Advisors)2025Q1$40.13+8.5%$47.3M
D.E. Shaw & Co.2025Q4$41.14+5.8%$250K

Who moved on this name in 2025Q4

Position changes reported for the latest quarter, grouped by direction.
New positions2
Added to2
Trimmed2
Exited1

Institutional ownership over time

Distinct super-investors holding this ticker · combined dollar value, by quarter.
QuarterHoldersCombined value
2025Q1
5
$46.7M
2025Q2
5
$73.3M
2025Q3
6
$121.8M
2025Q4
7
$215.8M

Who owns SION

7 super-investors · 2025Q4
Tracked stake
5.24M
shares
Combined value
$216M
% of shares outstanding
shares-out unknown
Quarter action mix
New2Added2Trim2Held1
#ManagerSharesValue
1Andreas Halvorsen
Viking Global
3.20M$131M
2Ken Griffin
Citadel Advisors
1.09M$45M
3T. Rowe Price831.4K$34M
4Izzy Englander
Millennium Mgmt
80.5K$3M
5Wellington Management38.3K$2M
6Two Sigma Investments6.4K$263K
7D.E. Shaw & Co.5.7K$236K

Recent moves

20 transactions
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