Ticker · CUSIP 74006W207

PRAX

PRAXIS PRECISION MEDICINES I

Healthcare·Biotechnology

···Share

Holders (tracked)

Combined shares

2,301,012

Combined value

$678.20M

Last close

$342.50

Quarter

2025Q4

Price is +16.2% vs the avg quarter-end implied price across tracked holders.

Price · 1Y$342.50+308.71 (+913.61%)H $347.55 · L $33.79 · Avg Vol 595K

Position opened

Tracked holders · last 8 quarters

+9 vs previous quarter over the last 8.

SEC event timeline

19 events

D.E. Shaw & Co. added2026-02-17
+17,685 shares · 2025Q4
Position
Ken Griffin (Citadel Advisors) added2026-02-17
+27,119 shares · 2025Q4
Position
Izzy Englander (Millennium Mgmt) added2026-02-17
+3,900 shares · 2025Q4
Position
Steve Cohen (Point72) trimmed2026-02-17
−1,003,640 shares · 2025Q4
Position
T. Rowe Price trimmed2026-02-17
−217,503 shares · 2025Q4
Position
Wellington Management added2026-02-17
+115,321 shares · 2025Q4
Position
Paul Tudor Jones (Tudor Investment) opened position2026-02-17
+16,009 shares · 2025Q4
Position
AQR Capital Management added2026-02-17
+6,924 shares · 2025Q4
Position
Two Sigma Investments added2026-02-17
+17,590 shares · 2025Q4
Position
Renaissance Technologies opened position2026-02-12
+66,230 shares · 2025Q4
Position
Norges Bank (Norway SWF) opened position2026-02-10
+4,354 shares · 2025Q4
Position
Steve Cohen (Point72) added2025-11-14
+541,911 shares · 2025Q3
Position
Two Sigma Investments trimmed2025-11-14
−1,001 shares · 2025Q3
Position
D.E. Shaw & Co. added2025-11-14
+740 shares · 2025Q3
Position
T. Rowe Price trimmed2025-11-14
−469,585 shares · 2025Q3
Position
AQR Capital Management added2025-11-14
+7,324 shares · 2025Q3
Position
Wellington Management added2025-11-14
+5,360 shares · 2025Q3
Position
Norges Bank (Norway SWF) exited2025-11-13
−5,000 shares · 2025Q3
Position
Norges Bank (Norway SWF) trimmed2025-11-12
−27,005 shares · 2024Q3
Position

Insider activity

No insider transactions in the last 30 days.

View full insider history for PRAX →

Follow-the-investor returns

If you'd copied each holder of PRAX…

Cost basis inferred from each manager's quarter-over-quarter position changes. Sorted by % return on the position they're still holding.

Investor	First in	Cost basis	Return	Position value today
Renaissance Technologies	2023Q4	$38.30	+794.3%	$22.7M
Steve Cohen (Point72)	2023Q4	$47.76	+617.2%	$168.6M
Steve Cohen (Point72)	2023Q4	$47.76	+617.2%	$168.6M
T. Rowe Price	2024Q1	$51.77	+561.6%	$269.2M
Norges Bank (Norway SWF)	2024Q1	$75.59	+353.1%	$1.5M
AQR Capital Management	2024Q3	$109.13	+213.9%	$9.9M
Wellington Management	2024Q1	$211.81	+61.7%	$60.5M
Izzy Englander (Millennium Mgmt)	2023Q4	$233.69	+46.6%	$3.2M
Izzy Englander (Millennium Mgmt)	2023Q4	$233.69	+46.6%	$3.2M
Two Sigma Investments	2023Q4	$235.26	+45.6%	$7.9M
Ken Griffin (Citadel Advisors)	2023Q4	$256.32	+33.6%	$18.6M
Ken Griffin (Citadel Advisors)	2023Q4	$256.32	+33.6%	$18.6M
Ken Griffin (Citadel Advisors)	2023Q4	$256.32	+33.6%	$18.6M
D.E. Shaw & Co.	2024Q2	$261.83	+30.8%	$1.7M
D.E. Shaw & Co.	2024Q2	$261.83	+30.8%	$1.7M
D.E. Shaw & Co.	2024Q2	$261.83	+30.8%	$1.7M
Paul Tudor Jones (Tudor Investment)	2025Q4	$294.74	+16.2%	$719K
Paul Tudor Jones (Tudor Investment)	2025Q4	$294.74	+16.2%	$719K
Paul Tudor Jones (Tudor Investment)	2025Q4	$294.74	+16.2%	$719K

Who moved on this name in 2025Q4

Position changes reported for the latest quarter, grouped by direction.

New positions3

Renaissance Technologies
+66,230
$19.5M
Paul Tudor Jones (Tudor Investment)
+16,009
$4.7M
Norges Bank (Norway SWF)
+4,354
$1.3M

Added to6

Wellington Management
+115,321
$34.0M
Ken Griffin (Citadel Advisors)
+27,119
$8.0M
D.E. Shaw & Co.
+17,685
$5.2M
Two Sigma Investments
+17,590
$5.2M
AQR Capital Management
+6,924
$2.0M
Izzy Englander (Millennium Mgmt)
+3,900
$1.1M

Trimmed2

Steve Cohen (Point72)
−1,003,640
$295.8M
T. Rowe Price
−217,503
$64K

Exited0

—

Institutional ownership over time

Distinct super-investors holding this ticker · combined dollar value, by quarter.

Quarter	Holders	Shares	Combined value	Δ holders
2023Q4	8	990,221	$22.1M	—
2024Q1	11	2,007,685	$122.5M	+3
2024Q2	12	3,631,729	$150.2M	+1
2024Q3	12	2,723,032	$156.7M	—
2024Q4	11	2,372,140	$182.6M	-1
2025Q1	9	1,717,242	$65.0M	-2
2025Q2	9	2,549,042	$107.2M	—
2025Q3	10	2,660,223	$141.0M	+1
2025Q4	19	2,301,012	$678.2M	+9

Who owns PRAX

19 super-investors · 2025Q4

Tracked stake

2.30M

Combined value

$678M

% of shares outstanding

—

shares-out unknown

Quarter action mix

New5Added11Trim3

#	Manager	Shares	Value	% of book	Last action
1	T. Rowe Price	786.0K	$232M	0.0%	Trim−217.5K
2	Steve Cohen Point72	500.0K	$147M	0.2%	Trim−1.00M
3	Steve Cohen Point72	492.3K	$145M	0.2%	Trim−1.00M
4	Wellington Management	176.6K	$52M	0.0%	Added+115.3K
5	Renaissance Technologies	66.2K	$20M	0.0%	New+66.2K
6	Ken Griffin Citadel Advisors	54.2K	$16M	0.0%	Added+27.1K
7	Ken Griffin Citadel Advisors	50.0K	$15M	0.0%	Added+27.1K
8	D.E. Shaw & Co.	37.5K	$11M	0.0%	Added+17.7K
9	Ken Griffin Citadel Advisors	34.9K	$10M	0.0%	Added+27.1K
10	AQR Capital Management	28.8K	$8M	0.0%	Added+6.9K
11	Two Sigma Investments	23.1K	$7M	0.0%	Added+17.6K
12	Paul Tudor Jones Tudor Investment	16.0K	$5M	0.0%	New+16.0K
13	Izzy Englander Millennium Mgmt	9.3K	$3M	0.0%	Added+3.9K
14	Paul Tudor Jones Tudor Investment	7.0K	$2M	0.0%	New+16.0K
15	D.E. Shaw & Co.	5.0K	$1M	0.0%	Added+17.7K
16	D.E. Shaw & Co.	5.0K	$1M	0.0%	Added+17.7K
17	Norges Bank Norway SWF	4.4K	$1M	0.0%	New+4.4K
18	Izzy Englander Millennium Mgmt	2.6K	$766K	0.0%	Added+3.9K
19	Paul Tudor Jones Tudor Investment	2.1K	$619K	0.0%	New+16.0K

Recent moves

20 transactions

ADDTwo Sigma Investments
+17,590 · 2025Q4
ADDAQR Capital Management
+6,924 · 2025Q4
ADDWellington Management
+115,321 · 2025Q4
ADDD.E. Shaw & Co.
+17,685 · 2025Q4
ADDKen Griffin (Citadel Advisors)
+27,119 · 2025Q4
TRIMT. Rowe Price
−217,503 · 2025Q4
ADDIzzy Englander (Millennium Mgmt)
+3,900 · 2025Q4
NEWPaul Tudor Jones (Tudor Investment)
+16,009 · 2025Q4
TRIMSteve Cohen (Point72)
−1,003,640 · 2025Q4
NEWRenaissance Technologies
+66,230 · 2025Q4
NEWNorges Bank (Norway SWF)
+4,354 · 2025Q4
ADDWellington Management
+5,360 · 2025Q3
ADDAQR Capital Management
+7,324 · 2025Q3
ADDD.E. Shaw & Co.
+740 · 2025Q3
ADDSteve Cohen (Point72)
+541,911 · 2025Q3
TRIMTwo Sigma Investments
−1,001 · 2025Q3
TRIMT. Rowe Price
−469,585 · 2025Q3
SOLDNorges Bank (Norway SWF)
−5,000 · 2025Q3
TRIMNorges Bank (Norway SWF)
−27,005 · 2024Q3
SOLDIzzy Englander (Millennium Mgmt)
−69,181 · 2025Q2

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