Ticker · CUSIP 558868105

MDGL

MADRIGAL PHARMACEUTICALS INC

Healthcare·Biotechnology

···Share

Holders (tracked)

Combined shares

3,322,248

Combined value

$1.93B

Last close

$532.02

Quarter

2025Q4

Price is -8.6% vs the avg quarter-end implied price across tracked holders.

Price · 1Y$532.02+230.36 (+76.36%)H $602.83 · L $267.56 · Avg Vol 355K

Tracked holders · last 8 quarters

+6 vs previous quarter over the last 8.

SEC event timeline

25 events

John Paulson (Paulson & Co) trimmed2026-02-17
−200,001 shares · 2025Q4
Position
Ken Griffin (Citadel Advisors) trimmed2026-02-17
−12,238 shares · 2025Q4
Position
D.E. Shaw & Co. trimmed2026-02-17
−7,628 shares · 2025Q4
Position
AQR Capital Management added2026-02-17
+3,420 shares · 2025Q4
Position
Izzy Englander (Millennium Mgmt) added2026-02-17
+5,180 shares · 2025Q4
Position
T. Rowe Price trimmed2026-02-17
−38,861 shares · 2025Q4
Position
Wellington Management added2026-02-17
+56,947 shares · 2025Q4
Position
Ron Baron (Baron Capital / BAMCO) trimmed2026-02-17
−100 shares · 2025Q4
Position
Paul Tudor Jones (Tudor Investment) opened position2026-02-17
+5,285 shares · 2025Q4
Position
Steve Cohen (Point72) added2026-02-17
+85,202 shares · 2025Q4
Position
Ray Dalio (Bridgewater Associates) trimmed2026-02-13
−8,567 shares · 2025Q4
Position
Renaissance Technologies trimmed2026-02-12
−36,820 shares · 2025Q4
Position
Norges Bank (Norway SWF) opened position2026-02-10
+196,393 shares · 2025Q4
Position
Steve Cohen (Point72) trimmed2025-11-14
−69,644 shares · 2025Q3
Position
D.E. Shaw & Co. trimmed2025-11-14
−15,799 shares · 2025Q3
Position
AQR Capital Management added2025-11-14
+3,419 shares · 2025Q3
Position
Izzy Englander (Millennium Mgmt) trimmed2025-11-14
−9,037 shares · 2025Q3
Position
T. Rowe Price trimmed2025-11-14
−155,944 shares · 2025Q3
Position
Wellington Management added2025-11-14
+397,076 shares · 2025Q3
Position
John Paulson (Paulson & Co) trimmed2025-11-14
−182,000 shares · 2025Q3
Position
Ron Baron (Baron Capital / BAMCO) opened position2025-11-14
+2,600 shares · 2025Q3
Position
Norges Bank (Norway SWF) exited2025-11-13
−176,467 shares · 2025Q3
Position
Ray Dalio (Bridgewater Associates) opened position2025-11-13
+27,785 shares · 2025Q3
Position
Renaissance Technologies added2025-11-13
+109,846 shares · 2025Q3
Position
Norges Bank (Norway SWF) trimmed2025-11-12
−46,053 shares · 2024Q3
Position

Insider activity

No insider transactions in the last 30 days.

View full insider history for MDGL →

Follow-the-investor returns

If you'd copied each holder of MDGL…

Cost basis inferred from each manager's quarter-over-quarter position changes. Sorted by % return on the position they're still holding.

Investor	First in	Cost basis	Return	Position value today
T. Rowe Price	2018Q1	$236.47	+125.0%	$166.9M
John Paulson (Paulson & Co)	2023Q2	$237.50	+124.0%	$908.4M
Norges Bank (Norway SWF)	2018Q3	$284.83	+86.8%	$104.5M
AQR Capital Management	2018Q1	$429.81	+23.8%	$5.3M
Renaissance Technologies	2016Q3	$443.44	+20.0%	$44.6M
Ray Dalio (Bridgewater Associates)	2025Q3	$458.66	+16.0%	$10.2M
Ron Baron (Baron Capital / BAMCO)	2025Q3	$458.66	+16.0%	$1.3M
Wellington Management	2018Q2	$468.82	+13.5%	$245.5M
Steve Cohen (Point72)	2017Q4	$479.74	+10.9%	$2.7M
Steve Cohen (Point72)	2017Q4	$479.74	+10.9%	$2.7M
Steve Cohen (Point72)	2017Q4	$479.74	+10.9%	$2.7M
Ken Griffin (Citadel Advisors)	2016Q3	$484.49	+9.8%	$19.2M
Ken Griffin (Citadel Advisors)	2016Q3	$484.49	+9.8%	$19.2M
Ken Griffin (Citadel Advisors)	2016Q3	$484.49	+9.8%	$19.2M
D.E. Shaw & Co.	2017Q4	$498.85	+6.6%	$14.5M
D.E. Shaw & Co.	2017Q4	$498.85	+6.6%	$14.5M
D.E. Shaw & Co.	2017Q4	$498.85	+6.6%	$14.5M
Izzy Englander (Millennium Mgmt)	2016Q3	$509.95	+4.3%	$3.7M
Paul Tudor Jones (Tudor Investment)	2019Q4	$561.30	-5.2%	$266K
Paul Tudor Jones (Tudor Investment)	2019Q4	$561.30	-5.2%	$266K
Paul Tudor Jones (Tudor Investment)	2019Q4	$561.30	-5.2%	$266K

Who moved on this name in 2025Q4

Position changes reported for the latest quarter, grouped by direction.

New positions2

Norges Bank (Norway SWF)
+196,393
$114.4M
Paul Tudor Jones (Tudor Investment)
+5,285
$3.1M

Added to4

Steve Cohen (Point72)
+85,202
$49.6M
Wellington Management
+56,947
$33.2M
Izzy Englander (Millennium Mgmt)
+5,180
$3.0M
AQR Capital Management
+3,420
$2.0M

Trimmed7

John Paulson (Paulson & Co)
−200,001
$116.5M
Renaissance Technologies
−36,820
$21.4M
Ken Griffin (Citadel Advisors)
−12,238
$7.1M
Ray Dalio (Bridgewater Associates)
−8,567
$5.0M
D.E. Shaw & Co.
−7,628
$4.4M
Ron Baron (Baron Capital / BAMCO)
−100
$58K
T. Rowe Price
−38,861
$23K

Exited0

—

Institutional ownership over time

Distinct super-investors holding this ticker · combined dollar value, by quarter.

Quarter	Holders	Shares	Combined value	Δ holders
2022Q1	9	2,179,942	$10.95B	—
2022Q2	10	1,353,239	$7.93B	+1
2022Q3	12	1,423,967	$92.5M	+2
2022Q4	14	2,039,429	$591.9M	+2
2023Q1	16	1,799,558	$436.0M	+2
2023Q2	14	1,965,592	$454.1M	-2
2023Q3	16	2,564,444	$374.5M	+2
2023Q4	10	2,996,726	$693.4M	-6
2024Q1	16	4,359,969	$1.16B	+6
2024Q2	16	4,513,147	$1.26B	—
2024Q3	13	3,164,696	$630.9M	-3
2024Q4	14	3,203,077	$988.4M	+1
2025Q1	15	3,045,316	$1.01B	+1
2025Q2	16	3,374,768	$1.02B	+1
2025Q3	15	3,211,936	$1.47B	-1
2025Q4	21	3,322,248	$1.93B	+6

Who owns MDGL

21 super-investors · 2025Q4

Tracked stake

3.32M

Combined value

$1.93B

% of shares outstanding

—

shares-out unknown

Quarter action mix

New4Added6Trim11

#	Manager	Shares	Value	% of book	Last action
1	John Paulson Paulson & Co	1.71M	$994M	30.5%	Trim−200.0K
2	Wellington Management	461.4K	$269M	0.0%	Added+56.9K
3	T. Rowe Price	313.7K	$183M	0.0%	Trim−38.9K
4	Norges Bank Norway SWF	196.4K	$114M	0.0%	New+196.4K
5	Steve Cohen Point72	126.4K	$74M	0.1%	Added+85.2K
6	Ken Griffin Citadel Advisors	104.9K	$61M	0.0%	Trim−12.2K
7	D.E. Shaw & Co.	88.6K	$52M	0.0%	Trim−7.6K
8	Renaissance Technologies	83.9K	$49M	0.1%	Trim−36.8K
9	D.E. Shaw & Co.	77.8K	$45M	0.0%	Trim−7.6K
10	Ken Griffin Citadel Advisors	43.1K	$25M	0.0%	Trim−12.2K
11	Ken Griffin Citadel Advisors	36.1K	$21M	0.0%	Trim−12.2K
12	D.E. Shaw & Co.	27.3K	$16M	0.0%	Trim−7.6K
13	Ray Dalio Bridgewater Associates	19.2K	$11M	0.0%	Trim−8.6K
14	AQR Capital Management	10.0K	$6M	0.0%	Added+3.4K
15	Izzy Englander Millennium Mgmt	7.0K	$4M	0.0%	Added+5.2K
16	Steve Cohen Point72	5.3K	$3M	0.0%	Added+85.2K
17	Paul Tudor Jones Tudor Investment	5.3K	$3M	0.0%	New+5.3K
18	Steve Cohen Point72	5.0K	$3M	0.0%	Added+85.2K
19	Ron Baron Baron Capital / BAMCO	2.5K	$1M	0.0%	Trim−100
20	Paul Tudor Jones Tudor Investment	500	$291K	0.0%	New+5.3K
21	Paul Tudor Jones Tudor Investment	400	$233K	0.0%	New+5.3K

Recent moves

20 transactions

TRIMJohn Paulson (Paulson & Co)
−200,001 · 2025Q4
ADDWellington Management
+56,947 · 2025Q4
TRIMRon Baron (Baron Capital / BAMCO)
−100 · 2025Q4
ADDAQR Capital Management
+3,420 · 2025Q4
TRIMT. Rowe Price
−38,861 · 2025Q4
TRIMD.E. Shaw & Co.
−7,628 · 2025Q4
TRIMKen Griffin (Citadel Advisors)
−12,238 · 2025Q4
ADDSteve Cohen (Point72)
+85,202 · 2025Q4
NEWPaul Tudor Jones (Tudor Investment)
+5,285 · 2025Q4
ADDIzzy Englander (Millennium Mgmt)
+5,180 · 2025Q4
TRIMRay Dalio (Bridgewater Associates)
−8,567 · 2025Q4
TRIMRenaissance Technologies
−36,820 · 2025Q4
NEWNorges Bank (Norway SWF)
+196,393 · 2025Q4
TRIMSteve Cohen (Point72)
−69,644 · 2025Q3
TRIMIzzy Englander (Millennium Mgmt)
−9,037 · 2025Q3
TRIMD.E. Shaw & Co.
−15,799 · 2025Q3
TRIMT. Rowe Price
−155,944 · 2025Q3
ADDWellington Management
+397,076 · 2025Q3
TRIMJohn Paulson (Paulson & Co)
−182,000 · 2025Q3
NEWRon Baron (Baron Capital / BAMCO)
+2,600 · 2025Q3

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