Ticker · CUSIP 35168W103

GUTS

FRACTYL HEALTH INC

Healthcare·Biotechnology

···Share

Holders (tracked)

Combined shares

11,850,000

Combined value

$26.07M

Last close

$0.57

Quarter

2025Q4

Price is -74.1% vs the avg quarter-end implied price across tracked holders.

Price · 1Y$0.57-0.65 (-53.36%)H $2.88 · L $0.39 · Avg Vol 2.9M

Position opened

Tracked holders · last 8 quarters

+1 vs previous quarter over the last 8.

SEC event timeline

12 events

D.E. Shaw & Co. added2026-02-17
+1,148,455 shares · 2025Q4
Position
Ken Griffin (Citadel Advisors) trimmed2026-02-17
−1,553,371 shares · 2025Q4
Position
Two Sigma Investments opened position2026-02-17
+1,840,136 shares · 2025Q4
Position
Izzy Englander (Millennium Mgmt) added2026-02-17
+1,453,751 shares · 2025Q4
Position
Steve Cohen (Point72) trimmed2026-02-17
−1,822,826 shares · 2025Q4
Position
Renaissance Technologies added2026-02-12
+1,086,351 shares · 2025Q4
Position
AQR Capital Management exited2025-11-14
−64,700 shares · 2025Q3
Position
Izzy Englander (Millennium Mgmt) trimmed2025-11-14
−115,306 shares · 2025Q3
Position
Steve Cohen (Point72) opened position2025-11-14
+2,187,999 shares · 2025Q3
Position
D.E. Shaw & Co. opened position2025-11-14
+294,290 shares · 2025Q3
Position
Renaissance Technologies opened position2025-11-13
+776,700 shares · 2025Q3
Position
Norges Bank (Norway SWF) trimmed2025-11-12
−213,541 shares · 2024Q3
Position

Insider activity

No insider transactions in the last 30 days.

View full insider history for GUTS →

Follow-the-investor returns

If you'd copied each holder of GUTS…

Cost basis inferred from each manager's quarter-over-quarter position changes. Sorted by % return on the position they're still holding.

Investor	First in	Cost basis	Return	Position value today
Steve Cohen (Point72)	2024Q1	$1.63	-65.0%	$208K
Ken Griffin (Citadel Advisors)	2024Q1	$1.91	-70.1%	$130K
Renaissance Technologies	2024Q2	$1.99	-71.4%	$1.1M
D.E. Shaw & Co.	2025Q3	$2.08	-72.6%	$821K
Izzy Englander (Millennium Mgmt)	2024Q1	$2.09	-72.8%	$1.1M
Two Sigma Investments	2025Q4	$2.20	-74.1%	$1.0M
Lee Ainslie (Maverick Capital)	2024Q1	$7.40	-92.3%	$2.4M

Who moved on this name in 2025Q4

Position changes reported for the latest quarter, grouped by direction.

New positions1

Two Sigma Investments
+1,840,136
$4.0M

Added to3

Izzy Englander (Millennium Mgmt)
+1,453,751
$3.2M
D.E. Shaw & Co.
+1,148,455
$2.5M
Renaissance Technologies
+1,086,351
$2.4M

Trimmed2

Steve Cohen (Point72)
−1,822,826
$4.0M
Ken Griffin (Citadel Advisors)
−1,553,371
$3.4M

Exited0

—

Institutional ownership over time

Distinct super-investors holding this ticker · combined dollar value, by quarter.

Quarter	Holders	Shares	Combined value	Δ holders
2024Q1	6	6,480,808	$48.0M	—
2024Q2	6	5,827,435	$24.9M	—
2024Q3	6	5,387,785	$13.6M	—
2024Q4	4	5,091,814	$10.5M	-2
2025Q1	5	4,388,856	$5.2M	+1
2025Q2	3	4,836,165	$7.8M	-2
2025Q3	6	9,697,504	$15.4M	+3
2025Q4	7	11,850,000	$26.1M	+1

Who owns GUTS

7 super-investors · 2025Q4

Tracked stake

11.85M

Combined value

$26M

% of shares outstanding

—

shares-out unknown

Quarter action mix

New1Added3Trim2Held1

#	Manager	Shares	Value	% of book	Last action	8Q trend
1	Lee Ainslie Maverick Capital	4.25M	$9M	0.1%	Held
2	Renaissance Technologies	1.86M	$4M	0.0%	Added+1.09M
3	Izzy Englander Millennium Mgmt	1.86M	$4M	0.0%	Added+1.45M
4	Two Sigma Investments	1.84M	$4M	0.0%	New+1.84M	—
5	D.E. Shaw & Co.	1.44M	$3M	0.0%	Added+1.15M
6	Steve Cohen Point72	365.2K	$803K	0.0%	Trim−1.82M
7	Ken Griffin Citadel Advisors	229.0K	$504K	0.0%	Trim−1.55M

Recent moves

20 transactions

TRIMKen Griffin (Citadel Advisors)
−1,553,371 · 2025Q4
ADDD.E. Shaw & Co.
+1,148,455 · 2025Q4
NEWTwo Sigma Investments
+1,840,136 · 2025Q4
ADDIzzy Englander (Millennium Mgmt)
+1,453,751 · 2025Q4
TRIMSteve Cohen (Point72)
−1,822,826 · 2025Q4
ADDRenaissance Technologies
+1,086,351 · 2025Q4
NEWSteve Cohen (Point72)
+2,187,999 · 2025Q3
SOLDAQR Capital Management
−64,700 · 2025Q3
TRIMIzzy Englander (Millennium Mgmt)
−115,306 · 2025Q3
NEWD.E. Shaw & Co.
+294,290 · 2025Q3
NEWRenaissance Technologies
+776,700 · 2025Q3
TRIMNorges Bank (Norway SWF)
−213,541 · 2024Q3
ADDAQR Capital Management
+47,142 · 2025Q2
ADDIzzy Englander (Millennium Mgmt)
+511,825 · 2025Q2
SOLDT. Rowe Price
−11,313 · 2025Q2
NEWAQR Capital Management
+17,558 · 2025Q1
NEWIzzy Englander (Millennium Mgmt)
+11,148 · 2025Q1
NEWNorges Bank (Norway SWF)
+100,000 · 2024Q1
SOLDNorges Bank (Norway SWF)
−100,000 · 2025Q1
TRIMT. Rowe Price
−68,500 · 2024Q4

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