Ticker · CUSIP 24823R105

DNLI

DENALI THERAPEUTICS INC

Healthcare·Biotechnology

···Share

Holders (tracked)

Combined shares

27,399,421

Combined value

$452.37M

Last close

$20.57

Quarter

2025Q4

Price is +24.6% vs the avg quarter-end implied price across tracked holders.

Price · 1Y$20.57+7.83 (+61.46%)H $22.74 · L $12.74 · Avg Vol 1.7M

Tracked holders · last 8 quarters

+2 vs previous quarter over the last 8.

SEC event timeline

24 events

Ken Griffin (Citadel Advisors) added2026-02-17
+90,924 shares · 2025Q4
Position
Two Sigma Investments added2026-02-17
+163,885 shares · 2025Q4
Position
Izzy Englander (Millennium Mgmt) trimmed2026-02-17
−937,404 shares · 2025Q4
Position
Steve Cohen (Point72) trimmed2026-02-17
−819,535 shares · 2025Q4
Position
Wellington Management trimmed2026-02-17
−4,691 shares · 2025Q4
Position
Paul Tudor Jones (Tudor Investment) opened position2026-02-17
+53,683 shares · 2025Q4
Position
T. Rowe Price trimmed2026-02-17
−652,417 shares · 2025Q4
Position
AQR Capital Management added2026-02-17
+14,299 shares · 2025Q4
Position
Renaissance Technologies trimmed2026-02-12
−49,100 shares · 2025Q4
Position
Norges Bank (Norway SWF) opened position2026-02-10
+5,119,622 shares · 2025Q4
Position
Ken Fisher (Fisher Asset Mgmt) added2026-02-09
+957,907 shares · 2025Q4
Position
Baillie Gifford & Co added2026-01-23
+719,304 shares · 2025Q4
Position
Paul Tudor Jones (Tudor Investment) exited2025-12-09
−55,448 shares · 2025Q3
Position
Two Sigma Investments added2025-11-14
+246,992 shares · 2025Q3
Position
Wellington Management trimmed2025-11-14
−5,605,499 shares · 2025Q3
Position
T. Rowe Price trimmed2025-11-14
−2,013,927 shares · 2025Q3
Position
Izzy Englander (Millennium Mgmt) added2025-11-14
+406,670 shares · 2025Q3
Position
AQR Capital Management added2025-11-14
+2,922 shares · 2025Q3
Position
Steve Cohen (Point72) added2025-11-14
+305,588 shares · 2025Q3
Position
Norges Bank (Norway SWF) exited2025-11-13
−3,947,387 shares · 2025Q3
Position
Renaissance Technologies trimmed2025-11-13
−135,900 shares · 2025Q3
Position
Norges Bank (Norway SWF) trimmed2025-11-12
−426,402 shares · 2024Q3
Position
Ken Fisher (Fisher Asset Mgmt) added2025-11-12
+115,505 shares · 2025Q3
Position
Baillie Gifford & Co trimmed2025-10-31
−363,738 shares · 2025Q3
Position

Insider activity

No insider transactions in the last 30 days.

View full insider history for DNLI →

Follow-the-investor returns

If you'd copied each holder of DNLI…

Cost basis inferred from each manager's quarter-over-quarter position changes. Sorted by % return on the position they're still holding.

Investor	First in	Cost basis	Return	Position value today
Izzy Englander (Millennium Mgmt)	2017Q4	$15.22	+35.1%	$7.6M
Two Sigma Investments	2020Q2	$15.59	+31.9%	$8.8M
Steve Cohen (Point72)	2022Q3	$15.92	+29.2%	$35.0M
Norges Bank (Norway SWF)	2017Q4	$16.36	+25.7%	$105.3M
Ken Griffin (Citadel Advisors)	2019Q1	$16.48	+24.8%	$557K
Ken Griffin (Citadel Advisors)	2019Q1	$16.48	+24.8%	$557K
Ken Fisher (Fisher Asset Mgmt)	2024Q1	$17.08	+20.4%	$53.3M
Paul Tudor Jones (Tudor Investment)	2020Q2	$22.03	-6.6%	$1.1M
AQR Capital Management	2019Q2	$23.44	-12.2%	$791K
T. Rowe Price	2018Q1	$23.71	-13.3%	$80.6M
Wellington Management	2017Q4	$25.88	-20.5%	$1.1M
Renaissance Technologies	2019Q2	$26.65	-22.8%	$220K
Baillie Gifford & Co	2017Q4	$34.53	-40.4%	$253.2M

Who moved on this name in 2025Q4

Position changes reported for the latest quarter, grouped by direction.

New positions2

Norges Bank (Norway SWF)
+5,119,622
$84.5M
Paul Tudor Jones (Tudor Investment)
+53,683
$886K

Added to5

Ken Fisher (Fisher Asset Mgmt)
+957,907
$15.8M
Baillie Gifford & Co
+719,304
$11.9M
Two Sigma Investments
+163,885
$2.7M
Ken Griffin (Citadel Advisors)
+90,924
$1.5M
AQR Capital Management
+14,299
$236K

Trimmed5

Izzy Englander (Millennium Mgmt)
−937,404
$15.5M
Steve Cohen (Point72)
−819,535
$13.5M
Renaissance Technologies
−49,100
$811K
Wellington Management
−4,691
$77K
T. Rowe Price
−652,417
$11K

Exited0

—

Institutional ownership over time

Distinct super-investors holding this ticker · combined dollar value, by quarter.

Quarter	Holders	Shares	Combined value	Δ holders
2022Q1	12	30,540,613	$28.17B	—
2022Q2	14	30,778,496	$25.36B	+2
2022Q3	13	29,900,682	$917.7M	-1
2022Q4	16	35,454,637	$986.0M	+3
2023Q1	15	36,972,424	$851.8M	-1
2023Q2	14	37,343,792	$1.10B	-1
2023Q3	11	30,016,992	$619.3M	-3
2023Q4	11	30,493,575	$654.4M	—
2024Q1	14	39,920,102	$819.2M	+3
2024Q2	14	43,418,132	$1.01B	—
2024Q3	12	29,193,565	$850.4M	-2
2024Q4	10	19,219,611	$391.7M	-2
2025Q1	12	32,349,200	$439.8M	+2
2025Q2	14	34,356,595	$480.7M	+2
2025Q3	11	22,727,444	$330.0M	-3
2025Q4	13	27,399,421	$452.4M	+2

Who owns DNLI

13 super-investors · 2025Q4

Tracked stake

27.40M

Combined value

$452M

% of shares outstanding

—

shares-out unknown

Quarter action mix

New2Added6Trim5

#	Manager	Shares	Value	% of book	Last action
1	Baillie Gifford & Co	12.31M	$203M	0.2%	Added+719.3K
2	Norges Bank Norway SWF	5.12M	$85M	0.0%	New+5.12M
3	T. Rowe Price	3.92M	$65M	0.0%	Trim−652.4K
4	Ken Fisher Fisher Asset Mgmt	2.59M	$43M	0.0%	Added+957.9K
5	Steve Cohen Point72	1.70M	$28M	0.0%	Trim−819.5K
6	Ken Griffin Citadel Advisors	779.1K	$13M	0.0%	Added+90.9K
7	Two Sigma Investments	430.2K	$7M	0.0%	Added+163.9K
8	Izzy Englander Millennium Mgmt	369.8K	$6M	0.0%	Trim−937.4K
9	Wellington Management	54.5K	$901K	0.0%	Trim−4.7K
10	Paul Tudor Jones Tudor Investment	53.7K	$886K	0.0%	New+53.7K
11	AQR Capital Management	38.4K	$635K	0.0%	Added+14.3K
12	Ken Griffin Citadel Advisors	27.1K	$447K	0.0%	Added+90.9K
13	Renaissance Technologies	10.7K	$177K	0.0%	Trim−49.1K

Recent moves

20 transactions

TRIMWellington Management
−4,691 · 2025Q4
TRIMT. Rowe Price
−652,417 · 2025Q4
NEWPaul Tudor Jones (Tudor Investment)
+53,683 · 2025Q4
ADDAQR Capital Management
+14,299 · 2025Q4
TRIMSteve Cohen (Point72)
−819,535 · 2025Q4
ADDTwo Sigma Investments
+163,885 · 2025Q4
ADDKen Griffin (Citadel Advisors)
+90,924 · 2025Q4
TRIMIzzy Englander (Millennium Mgmt)
−937,404 · 2025Q4
TRIMRenaissance Technologies
−49,100 · 2025Q4
NEWNorges Bank (Norway SWF)
+5,119,622 · 2025Q4
ADDKen Fisher (Fisher Asset Mgmt)
+957,907 · 2025Q4
ADDBaillie Gifford & Co
+719,304 · 2025Q4
SOLDPaul Tudor Jones (Tudor Investment)
−55,448 · 2025Q3
ADDSteve Cohen (Point72)
+305,588 · 2025Q3
TRIMT. Rowe Price
−2,013,927 · 2025Q3
ADDTwo Sigma Investments
+246,992 · 2025Q3
TRIMWellington Management
−5,605,499 · 2025Q3
ADDIzzy Englander (Millennium Mgmt)
+406,670 · 2025Q3
ADDAQR Capital Management
+2,922 · 2025Q3
TRIMRenaissance Technologies
−135,900 · 2025Q3

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