Ticker · CUSIP 91678A107

UPB

UPSTREAM BIO INC
···Share
Holders (tracked)
11
Combined shares
4,431,894
Combined value
$119.79M
Last close
Quarter
2025Q4
Tracked holders · last 8 quarters
+4 vs previous quarter over the last 5.
1132024Q42025Q4

SEC event timeline

15 events
  1. +13,420 shares · 2025Q4
    13F
  2. +27,091 shares · 2025Q4
    13F
  3. +549 shares · 2025Q4
    13F
  4. +477,151 shares · 2025Q4
    13F
  5. +9,700 shares · 2025Q4
    13F
  6. +1,135 shares · 2025Q4
    13F
  7. −230,662 shares · 2025Q4
    13F
  8. +16,400 shares · 2025Q4
    13F
  9. +2,882,647 shares · 2025Q4
    13F
  10. +40,113 shares · 2025Q3
    13F
  11. +10,500 shares · 2025Q3
    13F
  12. +1,053 shares · 2025Q3
    13F
  13. −99,900 shares · 2025Q3
    13F
  14. +202 shares · 2025Q3
    13F
  15. −969,916 shares · 2025Q3
    13F

Insider activity

No insider transactions in the last 30 days.

Who moved on this name in 2025Q4

13F transactions reported for the latest quarter, grouped by direction.
New positions5
Trimmed1
Exited0

Institutional ownership over time

Distinct super-investors holding this ticker · combined dollar value, by quarter.
QuarterHoldersCombined value
2024Q4
3
$20.2M
2025Q1
4
$8.7M
2025Q2
4
$24.4M
2025Q3
7
$23.6M
2025Q4
11
$119.8M

Who owns UPB

11 super-investors · 2025Q4
Tracked stake
4.43M
shares
Combined value
$120M
% of shares outstanding
shares-out unknown
Quarter action mix
New6Added3Trim1Held1
#ManagerSharesValue
1Norges Bank
Norway SWF
2.88M$78M
2Wellington Management894.7K$24M
3Izzy Englander
Millennium Mgmt
517.3K$14M
4AQR Capital Management30.5K$828K
5D.E. Shaw & Co.27.1K$736K
6Renaissance Technologies16.4K$445K
7Ken Griffin
Citadel Advisors
13.4K$364K
8Two Sigma Investments10.5K$285K
9Ken Griffin
Citadel Advisors
10.0K$272K
10Steve Cohen
Point72
9.7K$263K
11T. Rowe Price19.6K$534

Recent moves

20 transactions
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