Ticker · CUSIP 462222100

IONS

IONIS PHARMACEUTICALS INC
Healthcare·Biotechnology
···Share
Holders (tracked)
18
Combined shares
15,908,591
Combined value
$1.02B
Last close
$75.26
Quarter
2025Q4
Tracked holders · last 8 quarters
+4 vs previous quarter over the last 8.
18132024Q12025Q4
Price is +17.1% vs the avg quarter-end implied price across tracked holders.

SEC event timeline

29 events
  1. Paul Tudor Jones (Tudor Investment) opened position2026-02-17
    +3,661 shares · 2025Q4
    13F
  2. AQR Capital Management added2026-02-17
    +11,947 shares · 2025Q4
    13F
  3. Ken Griffin (Citadel Advisors) trimmed2026-02-17
    −267,429 shares · 2025Q4
    13F
  4. D.E. Shaw & Co. trimmed2026-02-17
    −298,135 shares · 2025Q4
    13F
  5. Two Sigma Investments added2026-02-17
    +1,082,703 shares · 2025Q4
    13F
  6. Ron Baron (Baron Capital / BAMCO) added2026-02-17
    +11,000 shares · 2025Q4
    13F
  7. Izzy Englander (Millennium Mgmt) trimmed2026-02-17
    −686,308 shares · 2025Q4
    13F
  8. Steve Cohen (Point72) opened position2026-02-17
    +28,200 shares · 2025Q4
    13F
  9. T. Rowe Price added2026-02-17
    +258,155 shares · 2025Q4
    13F
  10. Wellington Management trimmed2026-02-17
    −328,486 shares · 2025Q4
    13F
  11. Ray Dalio (Bridgewater Associates) added2026-02-13
    +24,128 shares · 2025Q4
    13F
  12. Renaissance Technologies trimmed2026-02-12
    −263,107 shares · 2025Q4
    13F
  13. Cathie Wood (ARK Invest) trimmed2026-02-11
    −208,247 shares · 2025Q4
    13F
  14. Norges Bank (Norway SWF) opened position2026-02-10
    +320,160 shares · 2025Q4
    13F
  15. Ken Fisher (Fisher Asset Mgmt) added2026-02-09
    +135,405 shares · 2025Q4
    13F
  16. D.E. Shaw & Co. opened position2025-11-14
    +630,938 shares · 2025Q3
    13F
  17. AQR Capital Management opened position2025-11-14
    +6,815 shares · 2025Q3
    13F
  18. Izzy Englander (Millennium Mgmt) trimmed2025-11-14
    −1,869,957 shares · 2025Q3
    13F
  19. Steve Cohen (Point72) exited2025-11-14
    −292,647 shares · 2025Q3
    13F
  20. Two Sigma Investments trimmed2025-11-14
    −212,424 shares · 2025Q3
    13F
  21. T. Rowe Price trimmed2025-11-14
    −396,388 shares · 2025Q3
    13F
  22. Wellington Management added2025-11-14
    +243,035 shares · 2025Q3
    13F
  23. Ron Baron (Baron Capital / BAMCO) opened position2025-11-14
    +25,000 shares · 2025Q3
    13F
  24. Ray Dalio (Bridgewater Associates) opened position2025-11-13
    +43,578 shares · 2025Q3
    13F
  25. Renaissance Technologies added2025-11-13
    +216,000 shares · 2025Q3
    13F
  26. Norges Bank (Norway SWF) exited2025-11-13
    −450,254 shares · 2025Q3
    13F
  27. Ken Fisher (Fisher Asset Mgmt) opened position2025-11-12
    +6,210 shares · 2025Q3
    13F
  28. Norges Bank (Norway SWF) added2025-11-12
    +1,007,820 shares · 2024Q3
    13F
  29. Cathie Wood (ARK Invest) trimmed2025-11-12
    −269,103 shares · 2025Q3
    13F

Insider activity

No insider transactions in the last 30 days.
View full insider history for IONS →
Follow-the-investor returns
If you'd copied each holder of IONS…
Cost basis inferred from 13F share-delta history. Sorted by % return on the position they're still holding.
InvestorFirst inCost basisReturnPosition value today
Paul Tudor Jones (Tudor Investment)2016Q2$31.67+137.7%$276K
T. Rowe Price2016Q1$34.65+117.2%$224.9M
Steve Cohen (Point72)2016Q1$39.14+92.3%$1.1M
Steve Cohen (Point72)2016Q1$39.14+92.3%$1.1M
Izzy Englander (Millennium Mgmt)2016Q1$39.26+91.7%$7.0M
Wellington Management2016Q1$43.55+72.8%$471.2M
Cathie Wood (ARK Invest)2016Q4$45.67+64.8%$31.8M
Renaissance Technologies2016Q1$45.87+64.1%$16.8M
Two Sigma Investments2017Q2$55.09+36.6%$200.1M
D.E. Shaw & Co.2016Q1$64.46+16.8%$25.0M
Ray Dalio (Bridgewater Associates)2021Q2$66.50+13.2%$5.1M
Ron Baron (Baron Capital / BAMCO)2025Q3$69.60+8.1%$2.7M
AQR Capital Management2016Q1$70.55+6.7%$1.4M
Ken Griffin (Citadel Advisors)2016Q1$78.38-4.0%$5.2M
Ken Griffin (Citadel Advisors)2016Q1$78.38-4.0%$5.2M
Ken Griffin (Citadel Advisors)2016Q1$78.38-4.0%$5.2M
Ken Fisher (Fisher Asset Mgmt)2025Q3$78.51-4.1%$10.7M
Norges Bank (Norway SWF)2016Q1$3949.51-98.1%$24.1M

Who moved on this name in 2025Q4

13F transactions reported for the latest quarter, grouped by direction.
New positions3
Added to6
Trimmed6
Exited0
—

Institutional ownership over time

Distinct super-investors holding this ticker · combined dollar value, by quarter.
QuarterHoldersCombined value
2022Q1
13
$30.27B
2022Q2
15
$42.55B
2022Q3
14
$53.5M
2022Q4
15
$542.4M
2023Q1
14
$482.2M
2023Q2
15
$643.5M
2023Q3
13
$678.2M
2023Q4
13
$780.1M
2024Q1
13
$893.5M
2024Q2
15
$1.05B
2024Q3
13
$578.0M
2024Q4
12
$242.9M
2025Q1
12
$477.4M
2025Q2
12
$567.0M
2025Q3
14
$874.4M
2025Q4
18
$1.02B

Who owns IONS

18 super-investors · 2025Q4
Tracked stake
15.91M
shares
Combined value
$1.02B
% of shares outstanding
—
shares-out unknown
Quarter action mix
New4Added6Trim8
#ManagerSharesValue
1Wellington Management6.26M$495M
2Two Sigma Investments2.66M$210M
3Ken Griffin
Citadel Advisors
2.13M$169M
4Cathie Wood
ARK Invest
423.0K$33M
5D.E. Shaw & Co.332.8K$26M
6Norges Bank
Norway SWF
320.2K$25M
7Renaissance Technologies223.6K$18M
8Ken Fisher
Fisher Asset Mgmt
141.6K$11M
9Ken Griffin
Citadel Advisors
109.4K$9M
10Izzy Englander
Millennium Mgmt
93.3K$7M
11Ken Griffin
Citadel Advisors
69.0K$5M
12Ray Dalio
Bridgewater Associates
67.7K$5M
13Ron Baron
Baron Capital / BAMCO
36.0K$3M
14AQR Capital Management18.8K$1M
15Steve Cohen
Point72
14.1K$1M
16Steve Cohen
Point72
14.1K$1M
17Paul Tudor Jones
Tudor Investment
3.7K$290K
18T. Rowe Price2.99M$236K

Recent moves

20 transactions
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